In 1877, the H.W. Perot Import Firm, largest supplier of sugar in Baltimore at the time, had a large shipment impounded by the U.S. Government, which questioned its purity. The company hired Constantin Fahlberg (born in Tambov, Russia in 1850), an expert on sugar, to run tests and requested Johns Hopkins University Professor Ira Remsen (born in Harlem, NY in 1846) for use of the chemistry lab he managed. H.W. Perot also hired Remsen, asking him to provide a laboratory for Fahlberg’s tests.
Constantin Fahlberg |
Ira Remsen, Johns Hopkins Professor and President |
Fahlberg sat down to dinner, picked up a roll with his hand and bit into a remarkably sweet crust – the result of having spilled an experimental compound over his hands from earlier that day. Realizing that it had to have come from the laboratory, according to his statement in a Baltimore Sun article he rushed back to it and “proceeded to taste the contents of every beaker and evaporating dish on the lab table. Luckily for me, none contained any corrosive or poisonous liquid.” Finally, he found the source: an overboiled beaker in which sulfobenzoic acid had reacted to ultimately produce benzoic sulfinide which, to the taste, outsugared sugar.
Seal of the Fahlberg, List & Co. |
Chandler's Saccharin Pellets |
"Concentrated sweetness in handy form. One pellet equals one teaspoon of sugar. Dissolves instantly – No bitter after-taste; which is experienced from the user of cheaper, inferior brands. Prescribed by doctors for persons unable to use sugar, also for reducing purposes. A non-fattening, non-nutritive sweetening agent."
By 1901, Monsanto was founded by John Francis Queeny, a 30-year veteran of the pharmaceutical industry, who gave the company his wife’s maiden name. Oddly enough, the company’s first product was saccharin (in 1902) despite his father-in-law being a wealthy financier of a sugar company based in St. Thomas - this became the first commercial production of saccharin in the United States. During the periods 1903 to 1905, Monsanto’s entire saccharin output was shipped (and later sold) to the growing soft drink company in Georgia, called Coca-Cola. Its use became widespread especially during World War I due to sugar shortages.
As early as 1907, the USDA investigated saccharin for being contradictory to the Pure Food and Drug Act, which had been enacted during President Theodore Roosevelt’s administration. Teddy Roosevelt (being a consumer of saccharin) opposed the investigation and was stated saying, “Anyone who says saccharin is injurious to health is an idiot” when people questioned its use as a sweetener. By 1917, the U.S. government filed suit over the safety of saccharin.
The safety of this now world-famous Baltimore-based discovery has been studied and written in volumes of literature and research. Interestingly enough, it was one of the co-founders himself (Ira Remsen was the Johns Hopkins University acting president) who was quoted by the Baltimore Sun as he lectured before the Public School Teacher’s Association on an evening in February 1890, “It may interest you to learn that saccharin was discovered about ten years ago in the chemical laboratory of the Johns Hopkins University, and that it is now manufactured on the large scale in Germany. It is an open question whether its side effects upon the system are injurious or not.”
Although it was possibly stated with vengeance over not being credited for its discovery within patent or public venues, perhaps this forewarning by the true co-inventor might be the best input in determining your own opinion about its safeness
Here in Baltimore, after his death in 1927, Dr. Ira Remsen’s ashes were placed behind a plaque in Remsen Hall on the Homewood Campus of saccharin’s discovery location at Johns Hopkins University. Dr. Constantine Fahlberg died in Aug 1910 and is buried at Novodevichy Cemetery, Moscow, Russia.
(Other Sources for this blogpost courtesy of: Chemical Heritage Magazine, Wikipedia, and Baltimore Sun articles)